Optimizing Oral Controlled Release Drug Delivery Systems Using Experimental Designs
نویسندگان
چکیده
منابع مشابه
LITERATURE ON CONTROLLED RELEASE DRUG DELIVERY SYSTEMS (MICROCAPSULES AND MATRIX TABLETS) Controlled release drug delivery systems
Controlled release drug delivery systems 1 are those dosage formulations designed to release an active ingredient at rates, which differ significantly from their corresponding conventional dosage forms. The controlled release drug delivery systems are aimed at controlling the rate of drug delivery, sustaining the duration of therapeutic activity and/or targeting the delivery of the drug to a ti...
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The purpose of this review article is to characterize all of the parameters regarding the types, polymers used, and release kinetics of matrix tablets. Matrix system was the earliest oral extended release platform for medicinal use. Matrix tablets are most commonly used methods to modulate the release profile of drugs. They are much desirable and preferred for such therapy because they o...
متن کاملDesign of Controlled- Release Drug Delivery Systems
22.1 PHYSICOCHEMICAL PROPERTIES OF 22.7 BIODEGRADABLE/ERODIBLE DRUG 22.2 DELIVERY SYSTEMS 22.9 22.2 ROUTES OF DRUG 22.8 OSMOTIC PUMP 22.10 ADMINISTRATION 22.3 22.9 ION EXCHANGE RESINS 22.11 22.3 PHARMACOLOGICAL AND 22.10 NEW MACROMOLECULAR DELIVERY BIOLOGICAL EFFECTS 22.4 APPROACHES 22.12 22.4 PRODRUG 22.4 22.11 CONCLUSION 22.14 22.5 DIFFUSION-CONTROLLED DELIVERY REFERENCES 22.14 SYSTEMS 22.5 2...
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Over the past decades, the treatment of illness has been accomplished by administering drugs to the human body via various pharmaceutical dosage forms, like tablets. These traditional pharmaceutical products are still commonly seen today in the prescription and over-the-counter drug marketplace. To achieve and maintain the drug concentration in the body within the therapeutic range required for...
متن کاملKinetic modeling on drug release from controlled drug delivery systems.
In this paper we review the mathematical models used to determine the kinetics of drug release from drug delivery systems. The quantitative analysis of the values obtained in dissolution/release rates is easier when mathematical formulae are used to describe the process. The mathematical modeling can ultimately help to optimize the design of a therapeutic device to yield information on the effi...
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ژورنال
عنوان ژورنال: Intellectual Property Rights: Open Access
سال: 2015
ISSN: 2375-4516
DOI: 10.4172/2375-4516.1000142